NR3C1 Antibody - N-terminal region : FITC (ARP31090_P050-FITC)
Selected Variant
ARP31090_P050-FITC
Size: 100 µL
Product Specifications
Gene Name
Nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
Gene Aliases
GR, GCR, GRL, GCCR, GCRST
Gene ID
2908
Swiss Prot
P04150
Accession Number
NP_001018086
Host
Rabbit
Reactivity
Human, Mouse, Rat, Cow, Horse, Pig, Rabbit, Sheep
Immunogen
The immunogen is a synthetic peptide directed towards the N terminal region of human NR3C1
Target
NR3C1 is a receptor for glucocorticoids that can act as both a transcription factor and as a regulator of other transcription factors. This protein can also be found in heteromeric cytoplasmic complexes along with heat shock factors and immunophilins. The protein is typically found in the cytoplasm until it binds a ligand, which induces transport into the nucleus. Mutations in this gene are a cause of glucocorticoid resistance, or cortisol, resistance.
Partner Proteins
TTC5; HSP90AA1; TXN2; UBC; TXN; FKBP5; DCAF6; RABEP2; BRCC3; LARP7; GAPVD1; CD2AP; SF3A1; HNRNPR; TRIM28; HDAC1; MTA2; CCDC6; CENPB; TMF1; PPARG; STUB1; BAG1; RPS6KA5; NCOA1; POLR1D; NCOA2; SRA1; PRKDC; RAD54L2; MAGEA11; PPP5C; PPID; GNB2; GNB1; FKBP4; GN
Clonality
Polyclonal
Conjugation
FITC: Fluorescein Isothiocyanate
Type
Polyclonal Antibody
Applications
WB, IHC
Purification
Affinity Purified
Concentration
0.5 mg/ml
Homology
Cow: 79%; Horse: 79%; Human: 100%; Mouse: 79%; Pig: 79%; Rabbit: 86%; Rat: 86%; Sheep: 79%
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
86kDa
Shipping Conditions
Wet Ice
Protein Length
777
NCBI Gene Symbol
NR3C1
NCBI GB Accession Number
NR3C1
Host or Source
Rabbit
Protein Name
Glucocorticoid receptor
Nucleotide Accession Number
NM_001018076
Peptide Sequence
MDSKESLTPGREENPSSVLAQERGDVMDFYKTLRGGATVKVSASSPSLAV
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