TFCP2 Antibody - N-terminal region : Biotin (ARP31073_P050-Biotin)

Product Specifications

Gene Name

Transcription factor CP2

Gene Aliases

LSF, SEF, LBP1C, LSF1D, TFCP2C

Gene ID

7024

Swiss Prot

Q12800

Accession Number

NP_005644

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human TFCP2

Target

TFCP2 binds a variety of cellular and viral promoters including fibrinogen, alpha-globin, SV40 and HIV-1 promoters. Activation of the alpha-globin promoter in erythroid cells is via synergistic interaction with UBP1. It also functions as part of the SSP (stage selector protein) complex. TFCP2 facilitates the interaction of the gamma-globin genes with enhancer elements contained in the locus control region in fetal erythroid cells. It interacts by binding to the stage selector element (SSE) in the proximal gamma-globin promoter.

Partner Proteins

E2F8; NPEPL1; CDC73; MRPL11; KIAA1598; CBX8; TDRD1; CCDC94; ASAP3; C19orf73; FANCL; ZCCHC10; FAM64A; DNAJC27; TRAPPC12; POLL; TSPAN12; PLCB1; STMN2; MORF4L1; FARS2; EIF5B; PITPNM1; PPIG; GPANK1; BAG6; SUMO1; TCEA2; SDCBP; RBMS1; PSMD5; PPP3R2; PHF1; MRPL4

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 92%; Horse: 100%; Human: 100%; Mouse: 100%; Pig: 100%; Rabbit: 100%; Rat: 93%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.