TFCP2 Antibody - N-terminal region : FITC (ARP31073_P050-FITC)
Product Specifications
Gene Name
Transcription factor CP2
Gene Aliases
LSF, SEF, LBP1C, LSF1D, TFCP2C
Gene ID
7024
Swiss Prot
Q12800
Accession Number
NP_005644
Host
Rabbit
Reactivity
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig, Rabbit
Immunogen
The immunogen is a synthetic peptide directed towards the N terminal region of human TFCP2
Target
TFCP2 binds a variety of cellular and viral promoters including fibrinogen, alpha-globin, SV40 and HIV-1 promoters. Activation of the alpha-globin promoter in erythroid cells is via synergistic interaction with UBP1. It also functions as part of the SSP (stage selector protein) complex. TFCP2 facilitates the interaction of the gamma-globin genes with enhancer elements contained in the locus control region in fetal erythroid cells. It interacts by binding to the stage selector element (SSE) in the proximal gamma-globin promoter.
Partner Proteins
E2F8; NPEPL1; CDC73; MRPL11; KIAA1598; CBX8; TDRD1; CCDC94; ASAP3; C19orf73; FANCL; ZCCHC10; FAM64A; DNAJC27; TRAPPC12; POLL; TSPAN12; PLCB1; STMN2; MORF4L1; FARS2; EIF5B; PITPNM1; PPIG; GPANK1; BAG6; SUMO1; TCEA2; SDCBP; RBMS1; PSMD5; PPP3R2; PHF1; MRPL4
Clonality
Polyclonal
Conjugation
FITC: Fluorescein Isothiocyanate
Type
Polyclonal Antibody
Applications
WB
Purification
Affinity Purified
Concentration
0.5 mg/ml
Homology
Cow: 100%; Dog: 100%; Guinea Pig: 92%; Horse: 100%; Human: 100%; Mouse: 100%; Pig: 100%; Rabbit: 100%; Rat: 93%
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
57kDa
References & Citations
Randall, C.N., (er) Neurochem. Res. (2008) In press
Shipping Conditions
Wet Ice
Protein Length
502
NCBI Gene Symbol
TFCP2
NCBI GB Accession Number
TFCP2
Host or Source
Rabbit
Protein Name
Alpha-globin transcription factor CP2
Nucleotide Accession Number
NM_005653
Peptide Sequence
YSMSDVLALPIFKQEESSLPPDNENKILPFQYVLCAATSPAVKLHDETLT
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