NR3C2 Antibody - N-terminal region : HRP (ARP31008_P050-HRP)
Product Specifications
Gene Name
Nuclear receptor subfamily 3, group C, member 2
Gene Aliases
MR, MCR, MLR, NR3C2VIT
Gene ID
4306
Swiss Prot
P08235
Accession Number
NP_000892
Host
Rabbit
Reactivity
Human, Mouse, Rat, Cow, Dog, Horse, Pig, Rabbit
Immunogen
The immunogen is a synthetic peptide directed towards the N terminal region of human NR3C2
Target
NR3C2 is a receptor for both mineralocorticoids (MC) such as aldosterone and glucocorticoids (GC) such as corticosterone or cortisol. It binds to mineralocorticoid response elements (MRE) and transactivates target genes. The effect of MC is to increase io
Partner Proteins
RABAC1; RXRA; HSP90AA1; ACSL1; UBC; SRC; PPP5C; PPID; FKBP5; FKBP4; STUB1; AIP; TRIM24; NRIP1; DNAJC7; CAND1; SUMO1; UBE2I; EIF3I; PROX1; PIAS1; PIAS3; HSPA4; PTGES3; AR; NR3C1; ACTA1; ACTG1
Clonality
Polyclonal
Conjugation
HRP: Horseradish Peroxidase
Type
Polyclonal Antibody
Applications
WB
Purification
Affinity Purified
Concentration
0.5 mg/ml
Homology
Cow: 77%; Dog: 93%; Horse: 100%; Human: 100%; Mouse: 79%; Pig: 79%; Rabbit: 86%; Rat: 79%
Format
Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
107kDa
References & Citations
Caprio, M., (2008) Circ. Res. 102 (11), 1359-1367
Shipping Conditions
Wet Ice
Protein Length
984
NCBI Gene Symbol
NR3C2
NCBI GB Accession Number
NR3C2
Host or Source
Rabbit
Protein Name
Mineralocorticoid receptor
Nucleotide Accession Number
NM_000901
Peptide Sequence
METKGYHSLPEGLDMERRWGQVSQAVERSSLGPTERTDENNYMEIVNVSC
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