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RUNX1 Antibody - middle region : Biotin (ARP30954_P050-Biotin)

Product Specifications

Gene Name

Runt-related transcription factor 1

Gene Aliases

AML1, CBFA2, EVI-1, AMLCR1, PEBP2aB, CBF2alpha, AML1-EVI-1, PEBP2alpha

Gene ID

861

Swiss Prot

Q01196

Accession Number

NP_001001890

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human RUNX1

Target

Core binding factor (CBF) is a heterodimeric transcription factor that binds to the core element of many enhancers and promoters. RUNX1 is the alpha subunit of CBF and is thought to be involved in the development of normal hematopoiesis. Chromosomal trans

Partner Proteins

YAP1; UBC; HDAC11; SOX2; SMAD3; CTBP1; RUNX1; FOXP3; NCOR2; MYC; NOTCH1; UXT; CTBP2; KAT6A; PML; CREBBP; CBFB; PRMT1; HLA-DMA; HDAC2; HDAC1; CBFA2T3; RUNX1T1; CBFA2T2; ELAVL1; DNMT1; SPEN; RBM14; KMT2A; COPRS; HDAC3; TAL1; CDK1; SMARCC1; SMARCB1; SMARCA4

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

IHC, WB

Purification

Affinity Purified

Sample Type

There is BioGPS gene expression data showing that RUNX1 is expressed in PANC1

Concentration

0.5 mg/ml

Homology

Cow: 93%; Dog: 93%; Guinea Pig: 93%; Horse: 93%; Human: 100%; Mouse: 92%; Rabbit: 93%; Rat: 93%; Zebrafish: 77%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

49kDa

References & Citations

Takeshita, M., (2008) Leukemia 22 (6), 1241-1249

Shipping Conditions

Wet Ice

Protein Length

453

NCBI Gene Symbol

RUNX1

NCBI GB Accession Number

RUNX1

Host or Source

Rabbit

Protein Name

Runt-related transcription factor 1

Nucleotide Accession Number

NM_001001890

Peptide Sequence

ERSPPRILPPCTNASTGSALLNPSLPNQSDVVEAEGSHSNSPTNMAPSAR

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