PBX1 Antibody - N-terminal region : Biotin (ARP30948_P050-Biotin)
Product Specifications
Gene Name
Pre-B-cell leukemia homeobox 1
Gene Aliases
CAKUHED
Gene ID
5087
Swiss Prot
P40424
Accession Number
NP_002576
Host
Rabbit
Reactivity
Human, Mouse, Rat, Cow, Dog, Pig
Immunogen
The immunogen is a synthetic peptide directed towards the N terminal region of human PBX1
Target
PBX1 binds the sequence 5'-ATCAATCAA-3'. It acts as a transcriptional activator of PF4 in complex with MEIS1. It may be converted into a potent transcriptional activator by the (1;19) translocation. It also may have a role in steroidogenesis and, subsequently, sexual development and differentiation.
Partner Proteins
SMARCD3; HOXA1; UCHL3; MDM2; UBC; KAT2A; HOXC8; NEDD4L; ELAVL1; MEIS2; PDX1; CREBBP; MEIS1; SIN3B; HDAC3; POU2F1; HDAC1; SMARCA4; HOXA10; MYOD1; PBX2; PAX6; PKNOX1; MYH10; HOXD10; HOXD4; HOXB1; HOXB8; HOXA9; HOXA5; NR3C1; HOXD9; HOXB7
Clonality
Polyclonal
Conjugation
Biotin
Type
Polyclonal Antibody
Applications
WB
Purification
Affinity Purified
Concentration
0.5 mg/ml
Homology
Cow: 100%; Dog: 100%; Human: 100%; Mouse: 100%; Pig: 100%; Rat: 100%
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
47kDa
References & Citations
Wang, H., (2005) Mol. Genet. Metab. 86 (3), 384-391
Shipping Conditions
Wet Ice
Protein Length
430
NCBI Gene Symbol
PBX1
NCBI GB Accession Number
PBX1
Host or Source
Rabbit
Protein Name
Pre-B-cell leukemia transcription factor 1
Nucleotide Accession Number
NM_002585
Peptide Sequence
MDEQPRLMHSHAGVGMAGHPGLSQHLQDGAGGTEGEGGRKQDIGDILQQI
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