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TH Antibody - N-terminal region : Biotin (ARP30889_P050-Biotin)

Product Specifications

Gene Name

Tyrosine hydroxylase

Gene Aliases

TYH, DYT14, DYT5b

Gene ID

7054

Swiss Prot

P07101

Accession Number

NP_954986

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the n terminal region of human TH

Target

The specific function of the protein remains unknown. The protein encoded by this gene is involved in the conversion of tyrosine to dopamine. It is the rate-limiting enzyme in the synthesis of catecholamines, hence plays a key role in the physiology of adrenergic neurons. Mutations in this gene have been associated with autosomal recessive Segawa syndrome. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.

Partner Proteins

TYSND1; YWHAQ; MAPKAPK2; CDK11B; RPS6KA5; CAMK2G; MAPK3; PRKACA; YWHAB; YWHAZ; MAPK1; SNCA; CSNK2A1

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Cow: 91%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

58kDa

References & Citations

Sutherland, G., Am. J. Med. Genet. B Neuropsychiatr. Genet. 147B (4), 495-499

Shipping Conditions

Wet Ice

Protein Length

528

NCBI Gene Symbol

TH

NCBI GB Accession Number

TH

Host or Source

Rabbit

Protein Name

Tyrosine 3-monooxygenase

Nucleotide Accession Number

NM_199292

Peptide Sequence

GAPGPSLTGSPWPGTAAPAASYTPTPRSPRFIGRRQSLIEDARKEREAAV

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