CXCR4 Antibody - N-terminal region : FITC (ARP30799_P050-FITC)

CXCR4 is a CXC chemokine receptor specific for stromal cell-derived factor-1. The protein has 7 transmembrane regions and is located on the cell surface. It acts with the CD4 protein to support HIV entry into cells and is also highly expressed in breast cancer cells. Mutations in this gene have been associated with WHIM (warts, hypogammaglobulinemia, infections, and myelokathexis) syndrome. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.This gene encodes a CXC chemokine receptor specific for stromal cell-derived factor-1. The protein has 7 transmembrane regions and is located on the cell surface. It acts with the CD4 protein to support HIV entry into cells and is also highly expressed in breast cancer cells. Mutations in this gene have been associated with WHIM (warts, hypogammaglobulinemia, infections, and myelokathexis) syndrome. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

UBC; ITCH; nef; P4HB; CD4; env; MYBL2; ST13; ATP13A2; CXCL12; PTPN11; STAM; CAV1; SUMO4; HLA-C; SDC4; HSPA8; GNA13; STAT5B; SOCS3; SOCS1; CCR5; PTK2; STAT2; STAT1; JAK3; DPP4; PTPN6; VAV1; CXCR4; MYH9; PTPRC; JAK2; JAK1; GNAI1; ELANE; CTSG; ADRBK2; ARRB2

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.