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CHAT Antibody - C-terminal region : HRP (ARP30665_P050-HRP)

Selected Variant

ARP30665_P050-HRP

Size: 100 µL

Product Specifications

Gene Name

Choline O-acetyltransferase

Gene Aliases

CMS6, CMS1A, CMS1A2, CHOACTASE

Gene ID

1103

Swiss Prot

A2BDF5

Accession Number

NP_066264

Host

Rabbit

Reactivity

Human, Dog, Horse, Pig

Target

CHAT is an enzyme which catalyzes the biosynthesis of the neurotransmitter acetylcholine. This protein is a characteristic feature of cholinergic neurons, and changes in these neurons may explain some of the symptoms of Alzheimer disease. Mutations in this gene are associated with congenital myasthenic syndrome associated with episodic apnea. Multiple transcript variants encoding different isoforms have been found for this gene, and some of these variants have been shown to encode more than one isoform.

Partner Proteins

NEDD9; CAMK2A; CAMK2G; PRKCZ; PRKCG; PRKCD; PRKCE; PRKCB; PRKCA

Clonality

Polyclonal

Conjugation

HRP: Horseradish Peroxidase

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Dog: 100%; Horse: 100%; Human: 100%; Pig: 91%

Format

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

70kDa

Shipping Conditions

Wet Ice

Protein Length

630

NCBI Gene Symbol

CHAT

NCBI GB Accession Number

CHAT

Host or Source

Rabbit

Protein Name

CHAT protein EMBL AAI30618.1

Nucleotide Accession Number

NM_020984

Peptide Sequence

SSFHSCKETSSSKFAKAVEESLIDMRDLCSLLPPTESKPLATKEKATRPS

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