MAP3K8 Antibody - N-terminal region : Biotin (ARP30650_P050-Biotin)

Product Specifications

Gene Name

Mitogen-activated protein kinase kinase kinase 8

Gene Aliases

COT, EST, ESTF, TPL2, AURA2, MEKK8, Tpl-2, c-COT

Gene ID

1326

Swiss Prot

P41279

Accession Number

NP_005195

Host

Rabbit

Reactivity

Human, Mouse, Cow, Horse

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human MAP3K8

Target

MAP3K8 is a member of the serine/threonine protein kinase family. This kinase can activate both the MAP kinase and JNK kinase pathways. This kinase was shown to activate IkappaB kinases, and thus induce the nuclear production of NF-kappaB. This kinase was

Partner Proteins

RELA; MAP2K1; RIPK1; NFKB1; ACY3; STIP1; HSP90AA1; TAB2; TRAF6; TRAF2; CD40; TNIP2; Nedd4; MAP3K14; MAP2K4; BMPR2; CHUK; REL; AKT1; NFKB2; KSR2

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Cow: 75%; Horse: 87%; Human: 100%; Mouse: 85%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.