DYRK3 Antibody - N-terminal region : Biotin (ARP30647_P050-Biotin)
Product Specifications
Gene Name
Dual-specificity tyrosine- (Y) -phosphorylation regulated kinase 3
Gene Aliases
RED, REDK, DYRK5, hYAK3-2
Gene ID
8444
Swiss Prot
D3DT79
Accession Number
NP_001004023
Host
Rabbit
Reactivity
Human, Rat, Guinea Pig, Yeast
Immunogen
The immunogen is a synthetic peptide directed towards the N terminal region of human DYRK3
Target
This gene product belongs to the DYRK family of dual-specificity protein kinases that catalyze autophosphorylation on serine/threonine and tyrosine residues. The members of this family share structural similarity, however, differ in their substrate specificity, suggesting their involvement in different cellular functions. The encoded protein has been shown to autophosphorylate on tyrosine residue and catalyze phosphorylation of histones H3 and H2B in vitro. Alternatively spliced transcript variants encoding different isoforms have been identified.
Partner Proteins
DYRK3; SORL1; FBXO25; PRNP; NEDD4L
Clonality
Polyclonal
Conjugation
Biotin
Type
Polyclonal Antibody
Applications
WB
Purification
Affinity Purified
Sample Type
DYRK3 is supported by BioGPS gene expression data to be expressed in HT1080
Concentration
0.5 mg/ml
Homology
Guinea Pig: 83%; Human: 100%; Rat: 90%; Yeast: 80%
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
64kDa
Shipping Conditions
Wet Ice
Protein Length
568
NCBI Gene Symbol
DYRK3
NCBI GB Accession Number
DYRK3
Host or Source
Rabbit
Protein Name
Dual specificity tyrosine-phosphorylation-regulated kinase 3
Nucleotide Accession Number
NM_001004023
Peptide Sequence
EPPPPRRLNMTTEQFTGDHTQHFLDGGEMKVEQLFQEFGNRKSNTIQSDG
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