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CLK4 Antibody - N-terminal region : Biotin (ARP30645_P050-Biotin)

Selected Variant

ARP30645_P050-Biotin

Size: 100 µL

Product Specifications

Gene Name

CDC-like kinase 4

Gene Aliases

DKFZp686A20267

Gene ID

57396

Swiss Prot

Q9HAZ1

Accession Number

NP_065717

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Yeast

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human CLK4

Target

The protein encoded by this gene belongs to the CDC2-like protein kinase (CLK) family. This protein kinase can interact with and phosphorylate the serine- and arginine-rich (SR) proteins, which are known to play an important role in the formation of spliceosomes, and thus may be involved in the regulation of alternative splicing. Studies in the Israeli sand rat Psammomys obesus suggested that the ubiquitin-like 5 (UBL5/BEACON), a highly conserved ubiquitin-like protein, may interact with and regulate the activity of this kinase. Multiple alternatively spliced transcript variants have been observed, but the full-length natures of which have not yet been determined.

Partner Proteins

KPNA1; KRTAP10-3; KRTAP10-8; KRTAP10-9; KRTAP10-7; CLK4; SRRM2; AHCYL2; SUB1; RASA4; SRPK1; RNF181; CLASRP; UBL5; HSPB2

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Cow: 93%; Dog: 100%; Guinea Pig: 100%; Horse: 93%; Human: 100%; Mouse: 86%; Rabbit: 100%; Rat: 93%; Yeast: 91%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

57

Shipping Conditions

Wet Ice

Protein Length

481

NCBI Gene Symbol

CLK4

NCBI GB Accession Number

CLK4

Host or Source

Rabbit

Protein Name

Dual specificity protein kinase CLK4

Nucleotide Accession Number

NM_020666

Peptide Sequence

RSRRSSPKRKRNRHCSSHQSRSKSHRRKRSRSIEDDEEGHLICQSGDVLR

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