OAS1 Antibody - C-terminal region : Biotin (ARP30587_P050-Biotin)
Selected Variant
ARP30587_P050-Biotin
Size: 100 µL
Product Specifications
Gene Name
2'-5'-oligoadenylate synthetase 1, 40/46kDa
Gene Aliases
OIAS, IFI-4, OIASI, E18/E16
Gene ID
4938
Swiss Prot
P00973
Accession Number
NP_058132
Host
Rabbit
Reactivity
Human
Target
OAS1 is a member of the 2-5A synthetase family, essential proteins involved in the innate immune response to viral infection. It is induced by interferons and uses adenosine triphosphate in 2'-specific nucleotidyl transfer reactions to synthesize 2',5'-oligoadenylates (2-5As) . These molecules activate latent RNase L, which results in viral RNA degradation and the inhibition of viral replication. Mutations in this gene have been associated with host susceptibility to viral infection.
Partner Proteins
EXOC5; TRIM27; ACTN1; PRMT6; WBSCR22; RPL30; HCVgp1
Clonality
Polyclonal
Conjugation
Biotin
Type
Polyclonal Antibody
Applications
IHC, WB
Purification
Affinity Purified
Sample Type
OAS1 is strongly supported by BioGPS gene expression data to be expressed in HEK293T, MCF7
Concentration
0.5 mg/ml
Homology
Human: 100%
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
46kDa
Shipping Conditions
Wet Ice
Protein Length
400
NCBI Gene Symbol
OAS1
NCBI GB Accession Number
OAS1
Host or Source
Rabbit
Protein Name
2'-5'-oligoadenylate synthase 1
Nucleotide Accession Number
NM_016816
Peptide Sequence
EAWLNYPCFKNWDGSPVSSWILLAESNSADDETDDPRRYQKYGYIGTHEY
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