TLR2 Antibody - C-terminal region : Biotin (ARP30551_P050-Biotin)

Product Specifications

Gene Name

Toll-like receptor 2

Gene Aliases

TIL4, CD282

Gene ID

7097

Swiss Prot

O60603

Accession Number

NP_003255

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Goat, Guinea Pig, Horse, Sheep, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the C terminal region of human TLR2

Target

TLR2 is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This gene is expressed most abundantly in peripheral blood leukocytes, and mediates host response to Gram-positive bacteria and yeast via stimulation of NF-kappaB. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Partner Proteins

ATG16L1; IRF3; CREBBP; CLEC7A; CLEC4M; TIRAP; MAPK8IP3; TICAM1; TOLLIP; TLR10; TLR6; LY96; RIPK2; TRIP6; MYD88; RAC1; TLR1; IRAK1; HSP90B1; HRAS; SFTPA1; PIK3R1; HMGB1; CD14; TLR2

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

IHC, WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Cow: 91%; Dog: 85%; Goat: 85%; Guinea Pig: 79%; Horse: 92%; Human: 100%; Mouse: 91%; Rat: 92%; Sheep: 91%; Zebrafish: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.