RAD17 Antibody - N-terminal region : Biotin (ARP30546_P050-Biotin)
Product Specifications
Gene Name
RAD17 homolog (S. pombe)
Gene Aliases
CCYC, R24L, RAD24, HRAD17, RAD17SP
Gene ID
5884
Swiss Prot
O75943-2
Accession Number
NP_002864
Host
Rabbit
Reactivity
Human, Rat, Cow, Dog, Horse, Pig, Rabbit
Immunogen
The immunogen is a synthetic peptide directed towards the N terminal region of human RAD17
Target
RAD17 is highly similar to the gene product of Schizosaccharomyces pombe rad17, a cell cycle checkpoint gene required for cell cycle arrest and DNA damage repair in response to DNA damage. This protein shares strong similarity with DNA replication factor C (RFC), and can form a complex with RFCs. This protein binds to chromatin prior to DNA damage and is phosphorylated by ATR after the damage. This protein recruits the RAD1-RAD9-HUS1 checkpoint protein complex onto chromatin after DNA damage, which may be required for its phosphorylation.
Partner Proteins
USP20; UBC; PRMT6; CBX7; CBX6; RAD9A; CDH1; ATR; RFC1; H2AFX; FOXO3; ATM; CLSPN; ALK; RAD9B; POLE; HUS1; RAD1; NHP2L1; MCM7; RFC4; RFC5; RFC3; RFC2; POLE4; POLE3; POLE2; PRKDC
Clonality
Polyclonal
Conjugation
Biotin
Type
Polyclonal Antibody
Applications
WB
Purification
Affinity Purified
Concentration
0.5 mg/ml
Homology
Cow: 89%; Dog: 100%; Horse: 92%; Human: 100%; Pig: 100%; Rabbit: 100%; Rat: 89%
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
76kDa
Shipping Conditions
Wet Ice
Product Datasheet
Anti-RAD17 (ARP30546_P050-Biotin) antibody
Protein Length
670
NCBI Gene Symbol
RAD17
NCBI GB Accession Number
RAD17
Host or Source
Rabbit
Protein Name
Cell cycle checkpoint protein RAD17
Nucleotide Accession Number
NM_002873
Peptide Sequence
MNQVTDWVDPSFDDFLECSGVSTITATSLGVNNSSHRRKNGPSTLESSRF
Curated Selection
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