CRKL Antibody - middle region : HRP (ARP30524_P050-HRP)
Product Specifications
Gene ID
1399
Swiss Prot
P46109
Accession Number
NP_005198
Host
Rabbit
Reactivity
Human
Immunogen
The immunogen is a synthetic peptide directed towards the middle region of Human CRKL
Target
CRKL has been shown to activate the RAS and JUN kinase signaling pathways and transform fibroblasts in a RAS-dependent fashion. It is a substrate of the BCR-ABL tyrosine kinase and plays a role in fibroblast transformation by BCR-ABL. In addition, CRKL has oncogenic potential.
Partner Proteins
HUWE1; UBC; BAG3; PIK3R2; DOK1; CBL; LMNA; SHANK3; GAREM; BIK; AOX1; WAC; POLR1D; TENC1; KHDRBS1; PPFIBP2; ARHGEF5; YY1; RPL31; ERBB3; ERBB2; PHC2; BCAR1; RAPGEF1; EPS15; EGFR; ABL1; STAT5A; PIK3R1; EPOR; ELAVL1; MSL1; PLEKHA1; LTBP4; PLSCR1; NOTCH2; LAMA
Clonality
Polyclonal
Conjugation
HRP: Horseradish Peroxidase
Type
Polyclonal Antibody
Applications
WB
Purification
Affinity Purified
Sample Type
CRKL is strongly supported by BioGPS gene expression data to be expressed in K562
Concentration
0.5 mg/ml
Format
Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
34kDa
Shipping Conditions
Wet Ice
Product Datasheet
Anti-CRKL (ARP30524_P050-HRP) antibody
Protein Length
303
NCBI Gene Symbol
CRKL
NCBI GB Accession Number
CRKL
Host or Source
Rabbit
Protein Name
Crk-like protein
Nucleotide Accession Number
NM_005207
Peptide Sequence
RSSPHGKHGNRNSNSYGIPEPAHAYAQPQTTTPLPAVSGSPGAAITPLPS
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