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TERF1 Antibody - C-terminal region : HRP (ARP30358_P050-HRP)

Selected Variant

ARP30358_P050-HRP

Size: 100 µL

Product Specifications

Gene Name

Telomeric repeat binding factor (NIMA-interacting) 1

Gene Aliases

TRF, PIN2, TRF1, TRBF1, t-TRF1, hTRF1-AS

Gene ID

7013

Swiss Prot

P54274

Accession Number

NP_059523

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Horse, Pig, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the C-terminal region of Human TERF1

Target

This gene encodes a telomere specific protein which is a component of the telomere nucleoprotein complex. This protein is present at telomeres throughout the cell cycle and functions as an inhibitor of telomerase, acting in cis to limit the elongation of individual chromosome ends. The protein structure contains a C-terminal Myb motif, a dimerization domain near its N-terminus and an acidic N-terminus. Two transcripts of this gene are alternatively spliced products.

Partner Proteins

EP300; SKP1; UBC; ANXA8L1; FBXO4; U2AF1; U2AF2; KDM1A; TINF2; BTRC; TNKS; TCIRG1; SMAD9; BLM; ATM; TNKS2; PINX1; RLIM; DDX19B; PACSIN2; OGFR; TOMM34; WDR4; ARPP21; TRIM16; HEXIM1; PAICS; DNPH1; HMGN4; TUBB4B; TUBB3; AKR1A1; RTN3; PAK4; STUB1; DDX39A; DPP3

Clonality

Polyclonal

Conjugation

HRP: Horseradish Peroxidase

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Cow: 91%; Dog: 91%; Horse: 91%; Human: 100%; Mouse: 90%; Pig: 91%; Rabbit: 82%; Rat: 91%

Format

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

48kDa

Shipping Conditions

Wet Ice

Protein Length

439

NCBI Gene Symbol

TERF1

NCBI GB Accession Number

TERF1

Host or Source

Rabbit

Protein Name

Telomeric repeat-binding factor 1

Peptide Sequence

NLRSGVRKYGEGNWSKILLHYKFNNRTSVMLKDRWRTMKKLKLISSDSED

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