AKT2 Antibody - middle region : HRP (ARP30321_P050-HRP)

AKT2 belonging to a subfamily of serine/threonine kinases containing SH2-like (Src homology 2-like) domains. The gene encoding AKT2 was shown to be amplified and overexpressed in 2 of 8 ovarian carcinoma cell lines and 2 of 15 primary ovarian tumors. Overexpression contributes to the malignant phenotype of a subset of human ductal pancreatic cancers. AKT2 is a general protein kinase capable of phophorylating several known proteins.This gene is a putative oncogene encoding a protein belonging to a subfamily of serine/threonine kinases containing SH2-like (Src homology 2-like) domains. The gene was shown to be amplified and overexpressed in 2 of 8 ovarian carcinoma cell lines and 2 of 15 primary ovarian tumors. Overexpression contributes to the malignant phenotype of a subset of human ductal pancreatic cancers. The encoded protein is a general protein kinase capable of phophorylating several known proteins. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

CLIP3; CHUK; PLEKHO1; PRKCZ; UBC; EGFR; POLR1B; SNX27; PNPLA3; STEAP4; ABCG8; POFUT1; TMED2; NAMPT; SORBS2; SPRR2A; CCL14; PRKDC; MAP3K5; HSP90AA1; APOB; APOA1; APPL1; APP; FSHR; VIM; SKI; GRK5; SH3RF1; ESR1; TTC3; SETDB1; XIAP; AKT1S1; TRIB3; PDPK1; GSK3

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.