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HSPA9 Antibody - C-terminal region : HRP (ARP30175_P050-HRP)

Product Specifications

Gene Name

Heat shock 70kDa protein 9 (mortalin)

Gene Aliases

CSA, MOT, MOT2, SAAN, CRP40, EVPLS, GRP75, PBP74, GRP-75, HSPA9B, SIDBA4, MTHSP75, HEL-S-124m

Gene ID

3313

Swiss Prot

P38646

Accession Number

NP_004125

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the C terminal region of human HSPA9

Target

HSPA9 belongs to the heat shock protein 70 family which contains both heat-inducible and constitutively expressed members. The latter are called heat-shock cognate proteins. HSPA9 is a heat-shock cognate protein. This protein plays a role in the control of cell proliferation. It may also act as a chaperone.CSHL1 is a member of the somatotropin/prolactin family of hormones which play an important role in growth control. This particular family member is expressed in placental villi, although it was originally thought to be a pseudogene. In fact, alternative splicing suggests that the majority of the transcripts would be unable to express a secreted protein.The product encoded by this gene belongs to the heat shock protein 70 family which contains both heat-inducible and constitutively expressed members. The latter are called heat-shock cognate proteins. This gene encodes a heat-shock cognate protein. This protein plays a role in the control of cell proliferation. It may also act as a chaperone. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications. The protein encoded by this gene is an inositol 1,4,5-trisphosphate (InsP3) 5-phosphatase and contains a Sac domain. The activity of this protein is specific for phosphatidylinositol 4,5-bisphosphate and phosphatidylinositol 3,4,5-trisphosphate. Alternatively spliced transcript variants have been observed, but most of them are not thought to be protein-coding.

Partner Proteins

GPX7; FUS; CDKN2A; UBC; TP53; YKT6; CDKN1A; CDC20; CEP250; TUBGCP2; CEP57; AURKB; TUBG1; AURKA; SUMO2; SUMO3; NEDD1; SPRTN; CEP76; HAUS2; TUBGCP4; STAU1; GRSF1; NEDD8; MDM2; EED; RAP1GDS1; PFAS; GINS3; ATG3; OSGEP; BZW2; ABHD14A; TNFAIP8; FERMT2; AIP; CNB

Clonality

Polyclonal

Conjugation

HRP: Horseradish Peroxidase

Type

Polyclonal Antibody

Applications

IHC, IP, WB

Purification

Affinity Purified

Sample Type

HSPA9 is strongly supported by BioGPS gene expression data to be expressed in HEK293T

Concentration

0.5 mg/ml

Homology

Cow: 85%; Dog: 92%; Guinea Pig: 92%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%

Format

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

75kDa

References & Citations

Shi, M., (2008) J. Neuropathol. Exp. Neurol. 67 (2), 117-124

Shipping Conditions

Wet Ice

Protein Length

679

NCBI Gene Symbol

HSPA9

NCBI GB Accession Number

HSPA9

Host or Source

Rabbit

Protein Name

Stress-70 protein, mitochondrial

Nucleotide Accession Number

NM_004134

Peptide Sequence

GENIRQAASSLQQASLKLFEMAYKKMASEREGSGSSGTGEQKEDQKEEKQ

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