CCNB1 Antibody - C-terminal region : Biotin (ARP30161_P050-Biotin)
Product Specifications
Gene Name
Cyclin B1
Gene Aliases
CCNB
Gene ID
891
Swiss Prot
P14635
Accession Number
NP_114172
Host
Rabbit
Reactivity
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit
Immunogen
The immunogen is a synthetic peptide directed towards the C terminal region of human CCNB1
Target
CCNB1 is a regulatory protein involved in mitosis. CCNB1 complexes with p34 (cdc2) to form the maturation-promoting factor (MPF) .The protein encoded by this gene is a regulatory protein involved in mitosis. The gene product complexes with p34 (cdc2) to form the maturation-promoting factor (MPF) . Two alternative transcripts have been found, a constitutively expressed transcript and a cell cycle-regulated transcript, that is expressed predominantly during G2/M phase. The different transcripts result from the use of alternate transcription initiation sites.
Partner Proteins
CDC27; CDC20; CDH1; ANAPC11; FZR1; ANAPC4; SIRT1; BTRC; CDC16; UBC; CDKN1A; VCP; Samhd1; CKS2; CKS1B; RHOBTB3; CDK1; CDK5; CDK2; SQSTM1; PTMA; TP73; TP53BP1; POLA1; RB1; CDK7; HIST1H1B; CDC6; CCNB1IP1; MFN1; MARCH5; PRC1; HIST1H1A; SDHAF2; NDC80; CDT1; RP
Clonality
Polyclonal
Conjugation
Biotin
Type
Polyclonal Antibody
Applications
IP, WB
Purification
Affinity Purified
Sample Type
CCNB1 is supported by BioGPS gene expression data to be expressed in Jurkat
Concentration
0.5 mg/ml
Homology
Cow: 92%; Dog: 85%; Guinea Pig: 92%; Horse: 85%; Human: 100%; Mouse: 92%; Rabbit: 92%; Rat: 92%
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
48kDa
References & Citations
Zhao, M., (2006) Exp Oncol 28 (1), 44-48
Shipping Conditions
Wet Ice
Protein Length
433
NCBI Gene Symbol
CCNB1
NCBI GB Accession Number
CCNB1
Host or Source
Rabbit
Protein Name
G2/mitotic-specific cyclin-B1
Nucleotide Accession Number
NM_031966
Peptide Sequence
YTEESLLPVMQHLAKNVVMVNQGLTKHMTVKNKYATSKHAKISTLPQLNS
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