CCNB1 Antibody - C-terminal region : FITC (ARP30161_P050-FITC)
Product Specifications
Gene Name
Cyclin B1
Gene Aliases
CCNB
Gene ID
891
Swiss Prot
P14635
Accession Number
NP_114172
Host
Rabbit
Reactivity
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit
Immunogen
The immunogen is a synthetic peptide directed towards the C terminal region of human CCNB1
Target
CCNB1 is a regulatory protein involved in mitosis. CCNB1 complexes with p34 (cdc2) to form the maturation-promoting factor (MPF) .The protein encoded by this gene is a regulatory protein involved in mitosis. The gene product complexes with p34 (cdc2) to form the maturation-promoting factor (MPF) . Two alternative transcripts have been found, a constitutively expressed transcript and a cell cycle-regulated transcript, that is expressed predominantly during G2/M phase. The different transcripts result from the use of alternate transcription initiation sites.
Partner Proteins
CDC27; CDC20; CDH1; ANAPC11; FZR1; ANAPC4; SIRT1; BTRC; CDC16; UBC; CDKN1A; VCP; Samhd1; CKS2; CKS1B; RHOBTB3; CDK1; CDK5; CDK2; SQSTM1; PTMA; TP73; TP53BP1; POLA1; RB1; CDK7; HIST1H1B; CDC6; CCNB1IP1; MFN1; MARCH5; PRC1; HIST1H1A; SDHAF2; NDC80; CDT1; RP
Clonality
Polyclonal
Conjugation
FITC: Fluorescein Isothiocyanate
Type
Polyclonal Antibody
Applications
IP, WB
Purification
Affinity Purified
Sample Type
CCNB1 is supported by BioGPS gene expression data to be expressed in Jurkat
Concentration
0.5 mg/ml
Homology
Cow: 92%; Dog: 85%; Guinea Pig: 92%; Horse: 85%; Human: 100%; Mouse: 92%; Rabbit: 92%; Rat: 92%
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
48kDa
References & Citations
Zhao, M., (2006) Exp Oncol 28 (1), 44-48
Shipping Conditions
Wet Ice
Protein Length
433
NCBI Gene Symbol
CCNB1
NCBI GB Accession Number
CCNB1
Host or Source
Rabbit
Protein Name
G2/mitotic-specific cyclin-B1
Nucleotide Accession Number
NM_031966
Peptide Sequence
YTEESLLPVMQHLAKNVVMVNQGLTKHMTVKNKYATSKHAKISTLPQLNS
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