ELL Antibody - C-terminal region : Biotin (ARP30105_T100-Biotin)
Selected Variant
ARP30105_T100-Biotin
Size: 100 µL
Product Specifications
Gene Name
Elongation factor RNA polymerase II
Gene Aliases
MEN, ELL1, PPP1R68, C19orf17
Gene ID
8178
Swiss Prot
P55199
Accession Number
NP_006523
Host
Rabbit
Reactivity
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Zebrafish
Immunogen
The immunogen is a synthetic peptide directed towards the C terminal region of human ELL
Target
ELL was shown to encode a previously uncharacterized elongation factor that can increase the catalytic rate of RNA polymerase II transcription by suppressing transient pausing by polymerase at multiple sites along the DNA. Functionally, ELL resembles Elongin (SIII), a transcription elongation factor regulated by the product of the von Hippel-Lindau (VHL) tumor suppressor gene.
Partner Proteins
UBC; LOC100363176; SNF8; MCM2; Polr2e; Polr2l; Polr2h; Polr2d; Polr2a; Polr2c; Polr2i; Polr2b; Polr2j; Polr2g; Polr2f; EAF1; ICE2; AFF4; PPP1CA; ICE1; MED26; MLLT3; CDK9; TFPT; KMT2A; MLLT1; USPL1; EAF2; HNRNPU; TP53; ZHX1; SIRT2
Clonality
Polyclonal
Conjugation
Biotin
Type
Polyclonal Antibody
Applications
IHC, WB
Concentration
0.5 mg/ml
Homology
Cow: 100%; Dog: 100%; Guinea Pig: 86%; Horse: 100%; Human: 100%; Mouse: 86%; Rat: 93%; Zebrafish: 86%
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
68kDa
References & Citations
Wiederschain, D., (2003) Mol. Cell. Biol. 23 (12), 4230-4246
Shipping Conditions
Wet Ice
Protein Length
621
NCBI Gene Symbol
ELL
NCBI GB Accession Number
ELL
Host or Source
Rabbit
Protein Name
RNA polymerase II elongation factor ELL
Nucleotide Accession Number
NM_006532
Peptide Sequence
TQLDAQLRQLSQGSEEYETTRGQILQEYRKIKKTNTNYSQEKHRCEYLHS
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