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CBX4 Antibody - N-terminal region : Biotin (ARP30002_P050-Biotin)

Product Specifications

Gene Name

Chromobox homolog 4

Gene Aliases

PC2, NBP16

Gene ID

8535

Swiss Prot

O00257-2

Accession Number

NP_003646

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Rabbit, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human CBX4

Target

The polycomb group (PcG) protein HPC2, which functions as a transcriptional suppressor, is a candidate of KyoT2-binding proteins. Pc2 dramatically enhances CtBP sumoylation. Pc2 is a SUMO E3, and Polycomb Group bodies may be sumoylation centers.

Partner Proteins

Rnf111; SUMO1; NEDD8; CBS; BMI1; EED; RNF2; HECW2; SOX2; YWHAE; YWHAB; CCDC158; DIS3L2; HIST4H4; CBX2; PARP12; RNF213; ZKSCAN7; DCAF6; KDM3A; MYCBP2; ANKRD26; PSME3; TRANK1; CBX4; HIST1H2AB; YWHAZ; SKIL; NPM1; HIST1H2BB; GTF2I; PHC2; CSNK2B; CSNK2A2; CSNK

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

IHC, WB

Purification

Affinity Purified

Sample Type

CBX4 is supported by BioGPS gene expression data to be expressed in Jurkat

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 77%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

61kDa

References & Citations

Kagey, M.H., et al., (2003) Cell 113 (1), 127-137

Shipping Conditions

Wet Ice

Protein Length

560

NCBI Gene Symbol

CBX4

NCBI GB Accession Number

CBX4

Host or Source

Rabbit

Protein Name

E3 SUMO-protein ligase CBX4

Nucleotide Accession Number

NM_003655

Peptide Sequence

LLIAFQNRERQEQLMGYRKRGPKPKPLVVQVPTFARRSNVLTGLQDSSTD

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