Sanggenon F

Sanggenon F is a flavonoid compound derived from Morus alba var. multicaulis. It inhibits the differentiation of 3T3-L1 adipocytes and the production of nitric oxide (NO) in RAW264.7 cells induced by lipopolysaccharides (HY-D1056) and IFN-γ (IC50 of 19 nM) . Sanggenon F has potential application value in the fields of anti-inflammatory and metabolic diseases[1].

Product Specifications

CAS Number

[85889-03-8]

UNSPSC

12352005

Target

NO Synthase

Type

Natural Products

Related Pathways

Immunology/Inflammation

Applications

Metabolism-sugar/lipid metabolism

Field of Research

Metabolic Disease; Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/sanggenon-f.html

Purity

95.0

Smiles

O=C1C2=C(O)C=C(O)C=C2O[C@H](C3=CC=C(OC(C)(C=C4)C)C4=C3O)C1

Molecular Formula

C20H18O6

Molecular Weight

354.35

References & Citations

[1]Yang ZG, et al. Inhibitory effects of constituents from Morus alba var. multicaulis on differentiation of 3T3-L1 cells and nitric oxide production in RAW264.7 cells. Molecules. 2011 Jul 19;16 (7) :6010-22.