Anti-TNF alpha HRP
TNF-alpha is a cytokine produced by monocytes, macrophages, neutrophils, NK cells, CD4+ T cells and many transformed cells. It can be expressed as a 17 kDa free molecule, or as a 26 kDa membrane protein. TNF-alpha easily forms stable trimers, but also other multimeric complexes. In the immune system, it is an important regulator, which has cytolytic and cytostatic activity against a range of tumor cells, increases fibroblast proliferation and supports neutrophil chemotaxis and phagocytosis.
Product Specifications
Certification
RUO
Immunogen
Recombinant human TNF-alpha
Target Antigen
TNF alpha
Clone
MAb11
Applications
ELISA (QC tested), IHC-F
Concentration
0.2 mg/mL
Format
HRP
Buffer
Stabilizing phosphate buffered saline (PBS), pH 7.4, 0.01% thimerosal
References & Citations
Storage Conditions
Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.
Specificity
The mouse monoclonal antibody MAb11 recognizes human 17-26 kDa cytokine TNF-alpha (tumor necrosis factor alpha) .
Applications Notes
ELISA: HRP-conjugated MAb11 can be used as a detection antibody in combination with capture antibody MAb1.
Species
Pig, Human, Non-human primates
Isotype
Mouse IgG1 kappa
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