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Anti-Hu CD194 Purified

CD194 is a G-protein-coupled seven membrane-spanning transmembrane protein serving as a high affinity receptor for C-C type chemokines TARC (CCL17) and MDC (CCL22), and as a coreceptor for HIV. It is expressed by all CLA+ T cells regardless of their Th1 or Th2 phenotype, on activated Th2, Treg, and activated NK cells, basophils and macrophages. Blocking CD194 function can be used for treatment of inflammation.

Product Specifications

Certification

RUO

Reactivity

Human

Target Antigen

CD194

Clone

RHIQB002

Applications

FC (QC tested)

Concentration

1 mg/mL

Format

Purified

Buffer

Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

Storage Conditions

Store at 2-8°C. Do not freeze.

Specificity

The recombinant mouse monoclonal antibody rHIQB002 recognizes an extracellular epitope of human chemokine receptor CD194 (CCR4) .

Applications Notes

Flow cytometry: Recommended dilution: 0.5-4 μg/ml.

Isotype

Mouse IgG1

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