Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

BDP5290

BDP5290 is a potent inhibitor of both ROCK and MRCK with IC50s of 5 nM, 50 nM, 10 nM and 100 nM for ROCK1, ROCK2, MRCKα and MRCKβ, respectively.

Product Specifications

CAS Number

1817698-21-7

UNSPSC

12352005

Hazard Statement

H302-H315-H319

Target

ROCK

Type

Reference compound

Related Pathways

Cell Cycle/DNA Damage; Cytoskeleton; Stem Cell/Wnt; TGF-beta/Smad

Applications

Cancer-Kinase/protease

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/BDP5290.html

Purity

98.90

Solubility

DMSO : 12.5 mg/mL (ultrasonic)

Smiles

ClC(C(C(NC1=CNN=C1C2=NC=CC=C2)=O)=N3)=CN3C4CCNCC4

Molecular Formula

C17H18ClN7O

Molecular Weight

371.82

Precautions

P264-P270-P280-P302+P352-P305+P351+P338-P330-P362+P364-P501

References & Citations

[1]Gandalovi?ová A, et al. Migrastatics-Anti-metastatic and Anti-invasion Drugs: Promises and Challenges. Trends Cancer. 2017 Jun;3 (6) :391-406.|[2]Unbekandt M, et al. A novel small-molecule MRCK inhibitor blocks cancer cell invasion. Cell Commun Signal. 2014 Oct 5;12:54.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

ROCK1; ROCK2

Available Sizes

Frequently Asked Questions

More Discoveries

Explore Other Products

Browse additional items from our catalog

Cyclopentylmethanol
FC31824-01 25 g

Cyclopentylmethanol

Sign In for Pricing
View Details
Cyclopentylmethanol
FC31824-02 50 g

Cyclopentylmethanol

Sign In for Pricing
View Details
VEGF165, Recombinant, Human (Vascular Endothelial Growth Factor, VPF, Folliculostellate Cell-derived Growth Factor, Glioma-derived Endothelial Cell Mitogen) discontinued
361432-01 2 µg

VEGF165, Recombinant, Human (Vascular Endothelial Growth Factor, VPF, Folliculostellate Cell-derived Growth Factor, Glioma-derived Endothelial Cell Mitogen) discontinued

Sign In for Pricing
View Details
VEGF165, Recombinant, Human (Vascular Endothelial Growth Factor, VPF, Folliculostellate Cell-derived Growth Factor, Glioma-derived Endothelial Cell Mitogen) discontinued
361432-02 10 µg

VEGF165, Recombinant, Human (Vascular Endothelial Growth Factor, VPF, Folliculostellate Cell-derived Growth Factor, Glioma-derived Endothelial Cell Mitogen) discontinued

Sign In for Pricing
View Details
Anti-RBM42 Antibody Picoband® Fluoro550 Conjugated
A14229-1-Fluoro550 100 µg/Vial

Anti-RBM42 Antibody Picoband® Fluoro550 Conjugated

Sign In for Pricing
View Details
Lentiviral human KLF10 shRNA (UAS) - Lentiviral human KLF10 shRNA (UAS) plasmid
GTR15344266 1 Vial

Lentiviral human KLF10 shRNA (UAS) - Lentiviral human KLF10 shRNA (UAS) plasmid

Sign In for Pricing
View Details