113-O12B

113-O12B is a disulfide bond-containing ionizable cationic lipidoid. 113-O12B can be used in that generation of lipid nanoparticles (LNPs) for the delivery of mRNA[1].

Product Specifications

CAS Number

[2803699-72-9]

UNSPSC

12352200

Hazard Statement

H302, H315, H319, H335

Target

Liposome

Type

Biochemical Assay Reagents

Related Pathways

Metabolic Enzyme/Protease

Applications

Metabolism-sugar/lipid metabolism

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/113-o12b.html

Purity

99.79

Solubility

DMSO : 100 mg/mL (ultrasonic) |Ethanol : 6.67 mg/mL (ultrasonic)

Smiles

O=C(CCN(CCN(CCN(CCC(OCCSSCCCCCCCC)=O)CCC(OCCSSCCCCCCCC)=O)C)CCC(OCCSSCCCCCCCC)=O)OCCSSCCCCCCCC

Molecular Formula

C57H111N3O8S8

Molecular Weight

1223.03

Precautions

H302, H315, H319, H335

References & Citations

[1]Jinjin Chen, et al. Lipid nanoparticle-mediated lymph node-targeting delivery of mRNA cancer vaccine elicits robust CD8+ T cell response. Proc Natl Acad Sci U S A. 2022 Aug 23;119 (34) :e2207841119.