BAY39-5493
BAY39-5493 is a non-nucleoside inhibitor that inhibits HBV replication. BAY39-5493 inhibits viral DNA replication by preventing the formation of viral core particles (nucleocapsids) . The IC50 value of BAY39-5493 against HBV in stably transfected HepG2.2.15 cells is 0.03 μM[1].
Product Specifications
CAS Number
[247037-81-6]
UNSPSC
12352005
Hazard Statement
H302-H315-H319-H335
Target
HBV
Type
Reference compound
Related Pathways
Anti-infection
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/bay39-5493.html
Smiles
O=C(C1=C(C)N=C(C2=NC=CS2)N[C@H]1C3=CC=C(F)C=C3Cl)OCC
Molecular Formula
C17H15ClFN3O2S
Molecular Weight
379.84
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
References & Citations
[1]Deres K, et al. Inhibition of hepatitis B virus replication by drug-induced depletion of nucleocapsids[J]. Science, 2003, 299 (5608) : 893-896.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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