Cyclopyrimorate

Cyclopyrimorate, a highly effective bleaching herbicide for weed control in rice fields, targets homogentisate solanesyltransferase (HST) . HST is a downstream enzyme of 4-hydroxyphenylpyruvate dioxygenase in the plastoquinone (PQ) biosynthesis pathway[1][2].

Product Specifications

CAS Number

[499231-24-2]

UNSPSC

12352005

Hazard Statement

H302-H315-H319-H335

Target

Herbicide

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

COVID-19-immunoregulation

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/cyclopyrimorate.html

Concentration

10mM

Purity

98.90

Solubility

DMSO : 250 mg/mL (ultrasonic)

Smiles

O=C(OC1=CC(Cl)=NN=C1OC2=C(C=CC=C2C3CC3)C)N4CCOCC4

Molecular Formula

C19H20ClN3O4

Molecular Weight

389.83

Precautions

P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362-P403+P233-P405-P501

References & Citations

[1]Shino M, et al. In vivo and in vitro evidence for the inhibition of homogentisate solanesyltransferase by cyclopyrimorate. Pest Manag Sci. 2019 Nov 27.|[2]Shino M, et al. Action mechanism of bleaching herbicide cyclopyrimorate, a novel homogentisate solanesyltransferase inhibitor. J Pestic Sci. 2018 Nov 20;43 (4) :233-239.