MrgprX2 antagonist-5
Product Specifications
UNSPSC Description
MrgprX2 antagonist-5 is an MrgprX2 antagonist extracted from patent WO2020223255A1, example 16. MrgprX2 antagonist-5 can be used for the research of inflammatory disorders of the skin[1].
Target Antigen
Mas-related G-protein-coupled Receptor (MRGPR)
Type
Reference compound
Related Pathways
GPCR/G Protein
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/mrgprx2-antagonist-5.html
Solubility
DMSO : 20 mg/mL (ultrasonic;warming;heat to 60°C)
Smiles
O=S1(N=C(NCC2=NC=CC=C2F)NC3=C(C4=C(Cl)C=CC=C4)C=C(C=C31)F)=O
Molecular Weight
434.85
References & Citations
[1]BIGI S, et, al. 3-amino-4h-benzo[e][1,2,4]thiadiazine 1,1-dioxide derivatives as inhibitors of mrgx2. WO2020223255A1.|[2]Porebski G, et, al. Mas-Related G Protein-Coupled Receptor-X2 (MRGPRX2) in Drug Hypersensitivity Reactions. Front Immunol. 2018 Dec 20;9:3027.
Shipping Conditions
Room Temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-145195/MrgprX2-antagonist-5-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-145195/MrgprX2-antagonist-5-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
2527815-74-1
Available Sizes
Curated Selection
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