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BZAD-01

Product Specifications

UNSPSC Description

BZAD-01 is a potent, selective and orally active inhibitor of NMDA NR2B subunit, with a Ki of 72 nM. BZAD-01 can improve postural asymmetry as well as Apomorphine-induced rotation[1].

Target Antigen

iGluR

Type

Reference compound

Related Pathways

Membrane Transporter/Ion Channel;Neuronal Signaling

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/bzad-01.html

Purity

99.81

Solubility

DMSO : 100 mg/mL (ultrasonic)|Methanol : 250 mg/mL (ultrasonic)

Smiles

N=C(NCC1=C(C(F)(F)F)C=CC=C1)C2=CC=C(C=C2)OC(F)(F)F

Molecular Weight

362.27

References & Citations

[1]Truong L, et, al. Behavioural effects of a selective NMDA NR1A/2B receptor antagonist in rats with unilateral 6-OHDA+parafascicular lesions. Brain Res Bull. 2009 Feb 16;78(2-3):91-6.

Shipping Conditions

Room Temperature

Storage Conditions

4°C (Powder, protect from light)

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-121100/BZAD-01-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-121100/BZAD-01-SDS-MedChemExpress.pdf

Clinical Information

No Development Reported

CAS Number

305339-41-7

Available Sizes

Curated Selection

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