BZAD-01

BZAD-01 is a potent, selective and orally active inhibitor of NMDA NR2B subunit, with a Ki of 72 nM. BZAD-01 can improve postural asymmetry as well as Apomorphine-induced rotation[1].

Product Specifications

CAS Number

[305339-41-7]

UNSPSC

12352005

Target

IGluR

Type

Reference compound

Related Pathways

Membrane Transporter/Ion Channel; Neuronal Signaling

Applications

Neuroscience-Neurodegeneration

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/bzad-01.html

Purity

99.81

Solubility

DMSO : 100 mg/mL (ultrasonic) |Methanol : 250 mg/mL (ultrasonic)

Smiles

N=C(NCC1=C(C(F)(F)F)C=CC=C1)C2=CC=C(C=C2)OC(F)(F)F

Molecular Formula

C16H12F6N2O

Molecular Weight

362.27

References & Citations

[1]Truong L, et, al. Behavioural effects of a selective NMDA NR1A/2B receptor antagonist in rats with unilateral 6-OHDA+parafascicular lesions. Brain Res Bull. 2009 Feb 16;78 (2-3) :91-6.