L-Glutamic acid-5-13C
L-Glutamic acid-5-13C is the 13C-labeled L-Glutamic acid. L-Glutamic acid acts as an excitatory transmitter and an agonist at all subtypes of glutamate receptors (metabotropic, kainate, NMDA, and AMPA) . L-Glutamic acid shows a direct activating effect on the release of DA from dopaminergic terminals.
Product Specifications
CAS Number
[81202-00-8]
UNSPSC
12352211
Target
Apoptosis; Endogenous Metabolite; Ferroptosis; iGluR; Isotope-Labeled Compounds
Type
Isotope-Labeled Compounds
Related Pathways
Apoptosis; Membrane Transporter/Ion Channel; Metabolic Enzyme/Protease; Neuronal Signaling; Others
Applications
Neuroscience-Neurodegeneration
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/l-glutamic-acid-5-13c.html
Purity
98.0
Solubility
10 mM in DMSO
Smiles
O[13C](CC[C@H](N)C(O)=O)=O
Molecular Formula
C4 13CH9NO4
Molecular Weight
148.12
References & Citations
[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53 (2) :211-216.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported
Isoform
AMPA Receptor; NMDA Receptor
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