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NorA-IN-1

NorA-IN-1 (Compound 16) is a NorA inhibitor. NorA-IN-1 inhibits NorA efflux pump in everted membrane vesicles. NorA-IN-1 can be used for research of multidrug resistance[1].

Product Specifications

CAS Number

[1389310-69-3]

UNSPSC

12352005

Hazard Statement

H315, H319

Target

Bacterial

Type

Reference compound

Related Pathways

Anti-infection

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/nora-in-1.html

Purity

96.55

Solubility

DMSO : 40 mg/mL (ultrasonic; adjust pH to 2 with 1 M HCl)

Smiles

O=C(C1=CC=C(C=C1)O)/C=C/C2=C(OC)C=C(OC)C=C2OC

Molecular Formula

C18H18O5

Molecular Weight

314.33

Precautions

H315, H319

References & Citations

[1]Holler JG, et al. Chalcone inhibitors of the NorA efflux pump in Staphylococcus aureus whole cells and enriched everted membrane vesicles. Bioorg Med Chem. 2012 Jul 15;20 (14) :4514-21.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Curated Selection

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