NCGC00244536

NCGC00244536 is a potent KDM4B inhibitor with an IC50 of 10 nM.

Product Specifications

CAS Number

[2003260-55-5]

Product Name Alternative

KDM4B Inhibitor B3

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Histone Demethylase

Type

Reference compound

Related Pathways

Epigenetics

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/NCGC00244536.html

Purity

99.70

Solubility

DMSO : 36.67 mg/mL (ultrasonic)

Smiles

O=C(NCCCC1=CC=CC=C1)C2=CC=CC(C3=CC(O)=C4N=CC=CC4=C3)=C2

Molecular Formula

C25H22N2O2

Molecular Weight

382.45

Precautions

H302, H315, H319, H335

References & Citations

[1]Duan L, et al. KDM4/JMJD2 Histone Demethylase Inhibitors Block Prostate Tumor Growth by Suppressing the Expression of AR and BMYB-Regulated Genes. Chem Biol. 2015 Sep 17;22 (9) :1185-96.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

KDM4

Available Sizes

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

TL316633 1 Kit

NDUFA7 Human shRNA Plasmid Kit (Locus ID 4701)

Ask

View Details

AP51843PU-N 400 µL

GIPC (GIPC1) (N-term) Rabbit Polyclonal Antibody

Ask

View Details

F4212-91D 100 µg

Fibroblast Growth Factor 19 (FGF19)

Ask

View Details

ABP-S-052680 5 Plates

Human HCG Alpha Matched Antibody Pair Set [ABP-S-052680]

Ask

View Details

MBS9911264 Inquire

Donkey DDB1- and CUL4-Associated Factor 16 (C4ORF30) ELISA Kit

Ask

View Details

MF-0059969-01 10 mg

6-Acetyl-7-hydroxy-2,3-dimethylchromone

Ask

View Details