Annamycin
Annamycin is an antibiotic, that has high affinity for lipid membranes and can bypass the multidrug resistance protein-1 (MDR-1) mechanism of cellular drug resistance. Annamycin exhibits antitumor efficacy in multilamellar vesicles against solid tumor[1].
Product Specifications
CAS Number
[92689-49-1]
UNSPSC
12352005
Hazard Statement
H340-H350-H360
Target
Antibiotic
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Cancer; Infection
Assay Protocol
https://www.medchemexpress.com/annamycin.html
Smiles
O=C1C2=C(C(C3=CC=CC=C31)=O)C(O)=C(C4=C2O)C[C@@](C(CO)=O)(C[C@@H]4O[C@@]5(O[C@H]([C@@H]([C@H]([C@H]5I)O)O)C)[H])O
Molecular Formula
C26H25IO11
Molecular Weight
640.37
Precautions
P280-P405-P501
References & Citations
[1]Booser DJ, et al., Phase I study of liposomal annamycin. Cancer Chemother Pharmacol. 2000;46 (5) :427-32.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Phase 3
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