KDM4D-IN-1
KDM4D-IN-1 is a new histone lysine demethylase 4D (KDM4D) inhibitor with an IC50 value of 0.41±0.03 μM.
Product Specifications
CAS Number
[2098902-68-0]
UNSPSC
12352005
Hazard Statement
H315, H319, H335
Target
Histone Demethylase
Type
Reference compound
Related Pathways
Epigenetics
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/KDM4D-IN-1.html
Purity
98.82
Solubility
DMSO : 7.14 mg/mL (ultrasonic)
Smiles
OC1=NC2=C(C#N)C(C)=NN2C3=C1C=CC=N3
Molecular Formula
C11H7N5O
Molecular Weight
225.21
Precautions
H315, H319, H335
References & Citations
[1]Fang Z, et al. Discovery of pyrazolo[1,5-a]pyrimidine-3-carbonitrile derivatives as a new class of histone lysine demethylase 4D (KDM4D) inhibitors. Bioorg Med Chem Lett. 2017 Jul 15;27 (14) :3201-3204.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
KDM4
Available Sizes
Curated Selection
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