Rimeporide

Rimeporide (EMD-87580) is a potent and selective inhibitor of the Na+/H+ exchanger (NHE-1) .

Product Specifications

CAS Number

[187870-78-6]

Product Name Alternative

EMD-87580

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Na+/H+ Exchanger (NHE)

Type

Reference compound

Related Pathways

Membrane Transporter/Ion Channel

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/Rimeporide.html

Concentration

10mM

Purity

98.71

Solubility

DMSO : 20 mg/mL (ultrasonic; warming)

Smiles

O=C(NC(N)=N)C1=CC(S(=O)(C)=O)=C(S(=O)(C)=O)C=C1C

Molecular Formula

C11H15N3O5S2

Molecular Weight

333.38

Precautions

H302, H315, H319, H335

References & Citations

[1]F.Porte-Thomé, et al. Development of Rimeporide, a sodium-hydrogen exchanger (NHE-1) inhibitor, for patients with Duchenne muscular dystrophy. Neuromuscular Disorders. October 2015 Oct 25:259-260.

Shipping Conditions

Blue Ice

Storage Conditions

-20°C, 3 years (Powder)

Scientific Category

Reference compound1

Clinical Information

Phase 1

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