Rimeporide
Rimeporide (EMD-87580) is a potent and selective inhibitor of the Na+/H+ exchanger (NHE-1) .
Product Specifications
CAS Number
[187870-78-6]
Product Name Alternative
EMD-87580
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Na+/H+ Exchanger (NHE)
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/Rimeporide.html
Concentration
10mM
Purity
98.71
Solubility
DMSO : 20 mg/mL (ultrasonic; warming)
Smiles
O=C(NC(N)=N)C1=CC(S(=O)(C)=O)=C(S(=O)(C)=O)C=C1C
Molecular Formula
C11H15N3O5S2
Molecular Weight
333.38
Precautions
H302, H315, H319, H335
References & Citations
[1]F.Porte-Thomé, et al. Development of Rimeporide, a sodium-hydrogen exchanger (NHE-1) inhibitor, for patients with Duchenne muscular dystrophy. Neuromuscular Disorders. October 2015 Oct 25:259-260.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Phase 1
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