Flunixin
Flunixin is a cyclooxygenase (COX) inhibitor with IC50 values of 0.55 and 3.24 μM for COX-1 and COX-2, respectively. Flunixin shows anti-inflammatory effects[1][2].
Product Specifications
CAS Number
[38677-85-9]
Product Name Alternative
Sch 14714
UNSPSC
12352005
Hazard Statement
H301
Target
COX
Type
Reference compound
Related Pathways
Immunology/Inflammation
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/flunixin.html
Solubility
10 mM in DMSO
Smiles
O=C(C1=CC=CN=C1NC2=CC=CC(C(F)(F)F)=C2C)O
Molecular Formula
C14H11F3N2O2
Molecular Weight
296.24
Precautions
P264-P270-P405-P501
References & Citations
[1]Z Cheng, et al. Measurement of cyclooxygenase inhibition in vivo: a study of two non-steroidal anti-inflammatory drugs in sheep. Inflammation. 1998 Aug;22 (4) :353-66.|[2]Clare E Bryant, et al. Evaluation of the ability of carprofen and flunixin meglumine to inhibit activation of nuclear factor kappa B. Am J Vet Res. 2003 Feb;64 (2) :211-5.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Launched
Isoform
COX-1; COX-2
Curated Selection
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