Telaprevir-d4
Telaprevir-d4 is the deuterium labeled Telaprevir. Telaprevir (VX-950) is a highly selective, reversible, and potent peptidomimetic inhibitor of the HCV NS3-4A protease, the steady-state inhibitory constant (Ki) of Telaprevir is 7 nM against a genotype 1 (H strain) NS3 protease domain plus a NS4A cofactor peptide[1][2][3]. Telaprevir inhibits SARS-CoV-2 3CLpro activity[4].
Product Specifications
Product Name Alternative
VX-950-d4
UNSPSC
12352005
Target
HCV; HCV Protease; Isotope-Labeled Compounds; SARS-CoV
Type
Isotope-Labeled Compounds
Related Pathways
Anti-infection; Metabolic Enzyme/Protease; Others
Field of Research
Infection
Solubility
10 mM in DMSO
Smiles
O=C(NC1C([2H])([2H])C1([2H])[2H])C([C@H](CCC)NC([C@@H]2[C@]3([H])[C@](CCC3)([H])CN2C([C@H](C(C)(C)C)NC([C@H](C4CCCCC4)NC(C5=NC=CN=C5)=O)=O)=O)=O)=O
Molecular Formula
C36H49D4N7O6
Molecular Weight
683.87
References & Citations
Shipping Conditions
Room temperature
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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