Peptide 74

Peptide 74 is a synthetic peptide containing the prodomain sequence of matrix metalloproteinase (MMP) . Peptide 74 inhibits the activated form of the 72-kDa type IV collagenase in vitro[1].

Product Specifications

CAS Number

[132116-39-3]

UNSPSC

12352209

Target

MMP

Type

Peptides

Related Pathways

Metabolic Enzyme/Protease

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/peptide-74.html

Purity

98.50

Solubility

H2O : 100 mg/mL (ultrasonic)

Smiles

C[C@@H](O)[C@H](N)C(N[C@@H](CCSC)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CCCCN)C(N1[C@@H](CCC1)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CS)C(NCC(N[C@@H](CC(N)=O)C(N2[C@@H](CCC2)C(N[C@@H](CC(O)=O)C(N[C@@H](C(C)C)C(N[C@@H](C)C(N[C@H](C(O)=O)CC(N)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O

Molecular Formula

C62H107N23O20S2

Molecular Weight

1558.79

References & Citations

[1]A Melchiori, et al. Inhibition of tumor cell invasion by a highly conserved peptide sequence from the matrix metalloproteinase enzyme prosegment. Cancer Res. 1992 Apr 15;52 (8) :2353-6.|[2]P P Lee, et al. Functional role of matrix metalloproteinases (MMPs) in mammary epithelial cell development. J Cell Physiol. 2001 Jul;188 (1) :75-88.