Mouse Thrombopoietin

<strong>Mouse Thrombopoietin</strong>_x000D_ <strong>Catalog number:</strong> B2014426_x000D_ <strong>Lot number:</strong> Batch Dependent_x000D_ <strong>Expiration Date:</strong> Batch dependent_x000D_ <strong>Amount:</strong> 2 µg_x000D_ <strong>Molecular Weight or Concentration:</strong> 35 kDa -75 kDa_x000D_ <strong>Supplied as:</strong> Solution_x000D_ <strong>Applications:</strong> molecular tool for various biochemical applications_x000D_ <strong>Storage:</strong> ‚àí20¬∞C_x000D_ <strong>Keywords:</strong> TPO_x000D_ <strong>Grade:</strong> Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity &gt;18 MŒ©-cm) and are filtered through 0.22 um._x000D_ _x000D_ <strong>References:</strong>_x000D_ 1: Gao L, Decker M, Chen H, Ding L. Thrombopoietin from hepatocytes promotes hematopoietic stem cell regeneration after myeloablation Elife. 2021 Aug 31;10:e69894._x000D_ 2: Skoda RC. Thrombocytosis Hematology Am Soc Hematol Educ Program. 2009:159-67._x000D_ 3: Jackson CW. New insights into the regulation of megakaryocyte differentiation and platelet production derived from cloning of thrombopoietin and its receptor: surprises and unresolved questions as thrombopoietin proceeds through clinical trials J Lab Clin Med. 1998 Jun;131(6):480-4._x000D_ 4: Kieran MW, Perkins AC, Orkin SH, Zon LI. Thrombopoietin rescues in vitro erythroid colony formation from mouse embryos lacking the erythropoietin receptor Proc Natl Acad Sci U S A. 1996 Aug 20;93(17):9126-31._x000D_ 5: Nakamura-Ishizu A, Chin DWL, Matsumura T, Tan DQ, Mochizuki-Kashio M, Jianwen D, Suda T. Prolonged maintenance of hematopoietic stem cells that escape from thrombopoietin deprivation Blood. 2021 May 13;137(19):2609-2620._x000D_ 6: McDonald TP. Regulation of megakaryocytopoiesis by thrombopoietin Ann N Y Acad Sci. 1987;509:1-24._x000D_ 7: Drachman JG, Rojnuckarin P, Kaushansky K. Thrombopoietin signal transduction: studies from cell lines and primary cells Methods. 1999 Mar;17(3):238-49._x000D_ 8: Vannucchi AM, Migliaccio AR, Paoletti F, Chagraoui H, Wendling F. Pathogenesis of myelofibrosis with myeloid metaplasia: lessons from mouse models of the disease Semin Oncol. 2005 Aug;32(4):365-72._x000D_ 9: Alexander WS. Thrombopoietin and the c-Mpl receptor: insights from gene targeting Int J Biochem Cell Biol. 1999 Oct;31(10):1027-35._x000D_ <a href="https://pubmed.ncbi.nlm.nih.gov/35301648">10: Irshad S, Shabbir A, Aslam H, Akhtar T, Shahzad M. Carica papaya ameliorates thrombocytopenia through upregulation of Interleukin-11 and modulation of thrombopoietin in mouse model of carboplatin-induced myelosuppression Mol Biol Rep. 2022 Jun;49(6):4633-4641. </a>_x000D_ _x000D_ <strong>Products Related to Mouse Thrombopoietin can be found at</strong> <a href="https://moleculardepot.com/product-category/Proteins/"> Proteins</a>