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Olaparib-d5

Product Specifications

UNSPSC Description

Olaparib-d5 is a deuterium labeled Olaparib. Olaparib is a potent and oral PARP inhibitor[1].

Target Antigen

Autophagy; Mitophagy; PARP

Type

Isotope-Labeled Compounds

Related Pathways

Autophagy;Cell Cycle/DNA Damage;Epigenetics

Applications

Cancer-programmed cell death

Field of Research

Cancer

Purity

99.0

Solubility

10 mM in DMSO

Smiles

O=C1NN=C(CC2=CC=C(F)C(C(N3CCN(C(C4([2H])C([2H])([2H])C4([2H])[2H])=O)CC3)=O)=C2)C5=C1C=CC=C5

Molecular Weight

439.49

References & Citations

[1]Menear KA, et al. 4-[3-(4-cyclopropanecarbonylpiperazine-1-carbonyl)-4-fluorobenzyl]-2H-phthalazin-1-one: a novel bioavailable inhibitor of poly(ADP-ribose) polymerase-1. J Med Chem. 2008 Oct 23;51(20):6581-91.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Clinical Information

No Development Reported

CAS Number

2143107-56-4

Available Sizes

Curated Selection

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