Olaparib-d5
Product Specifications
UNSPSC Description
Olaparib-d5 is a deuterium labeled Olaparib. Olaparib is a potent and oral PARP inhibitor[1].
Target Antigen
Autophagy; Mitophagy; PARP
Type
Isotope-Labeled Compounds
Related Pathways
Autophagy;Cell Cycle/DNA Damage;Epigenetics
Applications
Cancer-programmed cell death
Field of Research
Cancer
Purity
99.0
Solubility
10 mM in DMSO
Smiles
O=C1NN=C(CC2=CC=C(F)C(C(N3CCN(C(C4([2H])C([2H])([2H])C4([2H])[2H])=O)CC3)=O)=C2)C5=C1C=CC=C5
Molecular Weight
439.49
References & Citations
[1]Menear KA, et al. 4-[3-(4-cyclopropanecarbonylpiperazine-1-carbonyl)-4-fluorobenzyl]-2H-phthalazin-1-one: a novel bioavailable inhibitor of poly(ADP-ribose) polymerase-1. J Med Chem. 2008 Oct 23;51(20):6581-91.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Clinical Information
No Development Reported
CAS Number
2143107-56-4
Available Sizes
Curated Selection
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