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ARD-2585

Product Specifications

UNSPSC Description

ARD-2585 is an exceptionally potent and orally active PROTAC degrader of androgen receptor[1].

Target Antigen

Androgen Receptor; PROTACs

Type

Reference compound

Related Pathways

PROTAC;Vitamin D Related/Nuclear Receptor

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/ard-2585.html

Smiles

O=C(N(C1C(NC(CC1)=O)=O)C2=O)C(C2=C3)=CC=C3N(C4)CC4N(CC5)CCN5C(C=C6)=CC=C6C(N[C@@H]7CC[C@@H](N(C)C8=CC=C(C#N)C(Cl)=C8)CC7)=O

Molecular Weight

763.28

References & Citations

[1]Weiguo Xiang. et al. Discovery of ARD-2585 as an Exceptionally Potent and Orally Active PROTAC Degrader of Androgen Receptor for the Treatment of Advanced Prostate Cancer. J Med Chem. 2021 Sep 23;64(18):13487-13509.

Shipping Conditions

Blue Ice

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-139436/ARD-2585-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-139436/ARD-2585-SDS-MedChemExpress.pdf

CAS Number

2757422-79-8

Available Sizes

Curated Selection

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