(+) -Perillyl alcohol
(+) -Perillyl alcohol is the enantiomer of S- (-) -Perillyl alcohol. (+) -Perillyl alcohol can inhibit the growth of polypeptides and block the cell cycle in the G0/G1 phase. (+) -Perillyl alcohol induces cell signaling that is associated with changes in cytoskeletal actin organization and reduced protein expression of growth regulatory proteins such as Ras and CDC2 kinase[1].
Product Specifications
CAS Number
57717-97-2
Product Name Alternative
(R) - (+) -Perillyl alcohol
UNSPSC
12352211
Hazard Statement
H315-H319-H320
Target
Ras
Type
Reference compound
Related Pathways
GPCR/G Protein; MAPK/ERK Pathway
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/plus-perillyl-alcohol.html
Smiles
CC([C@@H]1CCC(CO)=CC1)=C
Molecular Formula
C10H16O
Molecular Weight
152.23
Precautions
P264-P280-P302+P352-P305+P351+P338-P362
References & Citations
[1]Cerda SR, et al. R- (+) -perillyl alcohol-induced cell cycle changes, altered actin cytoskeleton, and decreased ras and p34 (cdc2) expression in colonic adenocarcinoma SW480 cells. J Nutr Biochem. 1999 Jan;10 (1) :19-30.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported
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