(+) -Perillyl alcohol

(+) -Perillyl alcohol is the enantiomer of S- (-) -Perillyl alcohol (HY-116514) . (+) -Perillyl alcohol can inhibit the growth of polypeptides and block the cell cycle in the G0/G1 phase. (+) -Perillyl alcohol induces cell signaling that is associated with changes in cytoskeletal actin organization and reduced protein expression of growth regulatory proteins such as Ras and CDC2 kinase[1].

Product Specifications

CAS Number

[57717-97-2]

Product Name Alternative

(R) - (+) -Perillyl alcohol

UNSPSC

12352211

Hazard Statement

H315-H319-H320

Target

Ras

Type

Reference compound

Related Pathways

GPCR/G Protein; MAPK/ERK Pathway

Applications

Cancer-Kinase/protease

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/plus-perillyl-alcohol.html

Smiles

CC([C@@H]1CCC(CO)=CC1)=C

Molecular Formula

C10H16O

Molecular Weight

152.23

Precautions

P264-P280-P302+P352-P305+P351+P338-P362

References & Citations

[1]Cerda SR, et al. R- (+) -perillyl alcohol-induced cell cycle changes, altered actin cytoskeleton, and decreased ras and p34 (cdc2) expression in colonic adenocarcinoma SW480 cells. J Nutr Biochem. 1999 Jan;10 (1) :19-30.