AUTAC2-2G
AUTAC2-2G is a second-generation AUTAC with a 100-fold increase in activity[1].
Product Specifications
UNSPSC
12352005
Target
AUTACs; Autophagy
Type
Reference compound
Related Pathways
Autophagy; PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/autac2-2g.html
Purity
99.46
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
CCC(C)(C(C(N1CCCC[C@H]1C(O[C@@H](C2=CC(NC(CCC(NCCCOCCOCCOCCCN3C=C(C=N3)C4=NC5=C(N4CC6=CC=C(C=C6)F)N=C(NC5=O)N)=O)=O)=CC=C2)CCC7=CC(OC)=C(C=C7)OC)=O)=O)=O)C
Molecular Formula
C59H75FN10O12
Molecular Weight
1135.29
References & Citations
[1]Daiki Takahashi, et al. Second-Generation AUTACs for Targeted Autophagic Degradation. J Med Chem. 2023, 66, 17.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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