Lipid 5

Lipid 5 is an amino lipid that affords efficient mRNA delivery in rodent and primate models. Lipid 5 shows optimal pharmacokinetics and non-toxic side effects[1].

Product Specifications

CAS Number

[2089251-33-0]

UNSPSC

12352200

Hazard Statement

H225, H350

Target

Liposome

Type

Biochemical Assay Reagents

Related Pathways

Metabolic Enzyme/Protease

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/lipid-5.html

Concentration

10mM

Purity

99.78

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

O=C(OC(CCCCCCCC)CCCCCCCC)CCCCCCCN(CCO)CCCCCCCC(OCCCCCCCCC)=O

Molecular Formula

C44H87NO5

Molecular Weight

710.17

Precautions

H225, H350

References & Citations

[1]Staci Sabnis, et al. A Novel Amino Lipid Series for mRNA Delivery: Improved Endosomal Escape and Sustained Pharmacology and Safety in Non-human Primates. Mol Ther. 2018 Jun 6;26 (6) :1509-1519.